Welcome to the Rebeiz Lab!
Our lab is focused on understanding how complex developmental programs that control morphology evolve. To do this, we study rapidly evolving traits of the Drosophila model system: pigmentation, male genitalia, and gene expression traits.
The lab--established in the Fall of 2010--is housed in the Life Sciences Annex in the Department of Biological Sciences at the University of Pittsburgh.
July 12, 2019
Our website for sharing expression data in the genitalia is now up! You can browse how your favorite transcription factors are expressed in the genitalia at flyterminalia.pitt.edu/
June 28, 2019
Our preprint on the cellular development of a morphological novelty is out! We describe how this novel structure of the D. melanogaster genitalia became attached to a pre-existing network of extracellular matrix. Congrats to grad student Sarah (Smith)! See preprint here.
June 27, 2019
Our new paper on the evolution of body coloration is now out in Current Biology! We isolated regulatory mutations in a Hox gene, but found that its effect on phenotype was complicated by four other genes that together make its effects invisible. Congratulations to grad student/postdoc Yang Liu!
June 26, 2019
Our preprint on the transcriptional landscape of the developing genitalia is out. This was the labor of love of three undergraduate authors under the leadership of postdocs Ben Vincent and Gavin Rice. See preprint here.
June 11, 2019
Our preprint on the naming of Drosophila melanogaster terminal structures is out! Congratulations to postdoc Gavin Rice, who led the consortium. We hope this will facilitate the integration of developmental, taxonomic, and evolutionary studies of genitalia!
January 7, 2019
How many phenotypes do regulatory mutations affect? See our dispatch in Current Biology which covers a new study from the Orgogozo lab here
October 3, 2018
Our review on connecting GRNs to morphogenesis and evolutionary change is out! Congrats to grad student Sarah Smith and collaborator Lance Davidson! See the paper here
July 20, 2018
Congratulations to Dr. Yang Liu on the successful defense of her PhD thesis!
July 11, 2018
Congratulations to postdoc Ben Vincent on the funding of his NIH NRSA fellowship!
January 3, 2018
A collaborative paper with the Williams Lab describing the evolutionary history of transcriptional regulatory connections in the yellow gene was published in Elife! Find it here.
July 22, 2017
Our paper describing new capabilities of the GenePalette tool is out at Developmental Biology. See it here
May 18, 2017
Our collaborative review with Miltos Tsiantis on the evolutionary origins of regulatory sequences, and their impact on morphological novelties is out. You can view it here.
May 1, 2017
We have released a new version of the GenePalette software tool. It includes capabilities to download orthologous sequences from the UCSC genome browser database to facilitate phylogenetic footprinting.
January, 26, 2017
Our new paper on how heterochrony may explain novel patterns of gene expression was published in Evolution & Development here. Congrats to undergrad Thomas Pham and team!
October 16, 2016
Check out our review on the evolution of Drosophila pigmentation traits that just appeared in Current Opinion in Insect Science
September 1, 2016
Mark was promoted to Associate Professor with tenure!
August 31, 2016
Good luck to Dr. Glassford in his postdoc at Columbia University
August 18, 2016
A collaborative paper with the Kopp lab was published in Current Biology!
May 31, 2016
Congratulations to Dr. Glassford on the successful defense of his thesis!
March 31, 2016:
Our very own Natalie Dall was awarded a 2016 Goldwater Fellowship!
October 6, 2015:
Natalie Dall was awarded the 2015-2016 Horowitz Fellowship!
September 14, 2015:
Bill's paper (with a little help from sundry lab members) was published on the cover of Developmental Cell!
August 24, 2015:
Our review on gene regulatory network evolution just appeared in Annual Reviews of Genomics and Human Genetics!
August 4, 2015:
Mark gave a talk at the Inaugural Pan Am Evo-Devo society meeting in Berkeley
June 26, 2015:
Winslow and Ali's paper on the inactivation of transcriptional silencer elements was published in PLoS Genetics!
May 1 2015:
The lab was awarded a new R01 in collaboration with Peter Andolfatto to study the evolution of pigmentation differences between D. yakuba and D. santomea!